Clinical guidelines «Rational use of nonsteroidal anti-inflammatory drugs (NSAIDs) in clinical practice»
نویسندگان
چکیده
منابع مشابه
Nonsteroidal anti-inflammatory drugs (NSAIDs), cyxlooxygenase-2 selective inhibitors (coxibs) and gastrointestinal harm: review of clinical trials and clinical practice
BACKGROUND Gastrointestinal harm, known to occur with NSAIDs, is thought to be lower with NSAID and gastroprotective agent, and with inhibitors selective to cyclooxygenase-2 (coxibs) at usual plasma concentrations. We examine competing strategies for available evidence of reduced gastrointestinal bleeding in clinical trials and combine this evidence with evidence from clinical practice on wheth...
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Nonsteroidal anti-inflammatory drugs (NSAIDs) are a diverse class of drugs commonly used for the treatment of inflammatory conditions, have been found to be highly effective in preventing and treating many types of cancers. However, toxicity from cyclooxygenase (COX) inhibition and the suppression of physiologically important prostaglandins limits their use for cancer chemoprevention and prompt...
متن کاملNonsteroidal Anti-inflammatory Drugs (NSAIDs) and Chemoprevention of Breast Cancer
Randall Harris, of Ohio State University, Columbus, Ohio, and colleagues presented very interesting results from a prospective study on the effects of anti-inflammatory agents in the chemoprevention of breast cancer in women enrolled in the Women's Health Initiative observational study. A total of 80,741 postmenopausal women (50-79 years of age) with no previous history of cancer (other than no...
متن کاملClinical pharmacology of nonsteroidal anti-inflammatory drugs in dogs.
OBJECTIVES To discuss the clinical pharmacology of currently licensed veterinary NSAIDs and to review gastrointestinal and renal adverse effects as well as drug-drug interactions that have been reported with these drugs. To review the use of NSAIDs in the peri-operative setting and their use in patients with osteoarthritis. To further review the reported effects of NSAIDs on canine articular ca...
متن کاملSelecting nonsteroidal anti-inflammatory drugs: pharmacologic and clinical considerations.
An increasing number of nonsteroidal anti-inflammatory drugs (NSAIDs) are available to treat a variety of conditions. There exist little comparative data examining efficacy for all NSAIDs for a particular illness. The major factors governing selection of these agents relate to the patient's condition and the drug's characteristics. Once efficacy has been established, selection of an NSAID is th...
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ژورنال
عنوان ژورنال: Modern Rheumatology Journal
سال: 2015
ISSN: 2310-158X,1996-7012
DOI: 10.14412/1996-7012-2015-1-4-23